Seven reasons you should attend SIGNAL 2025

April 29, 2025

We’re back, baby. 

For the first time since 2019, Twilio’s biggest event is back in San Francisco—returning to the city that helped build it, for the builders reimagining what’s ahead. And this year, SIGNAL 2025 is offering over 100 sessions tailored to a diverse range of builders, from marketers to developers. 

Whether you're interested in 10-minute lightning talks or 2-hour build-it-yourself workshops, you’ll have ample opportunity to architect the experience that fits your focus at this year’s SIGNAL. 

So, without further ado, here are seven reasons to be there when it all goes down: 

1. We built you an arcade—powered by your own data

Game on. This year, SIGNAL's Community Hall features the Twilio Arcade — a retro (and yet) futuristic arcade where every game you play lights up a live data journey. Scan into sessions, complete challenges, and watch as LED pixel trails track your moves across the room. It's part game, part visualization engine, showing how real-time customer signals flow through Twilio and Segment. And maybe—if you play your cards right—you'll unlock access to the (shhh…) secret backroom. 

Two people at a trade show booth, laughing and engaging with a computer screen.

2. Disney World… but for developers

SIGNAL’s developer experience is anything but surface level (and we built it that way). This year, you’ll build a Retrieval-Augmented Generation (RAG) chatbot using Twilio AI Assistants with no LangChain headaches required. Or maybe you’ll dive into how to integrate email into Flex in a hands-on lab, watching real-time customer data flow into Segment’s Unified Profiles. You can even get into the gritty mechanics of masked communications with Conversations and Voice APIs, including number pools to session orchestration. Factor in live coding labs, hallway debugging with Twilio engineers, and spontaneous whiteboarding that leads to your next big idea, and you’ll quickly realize it’s a small world after all (when you’re building with the right tools!).

3. Learn what Spotify, Nextdoor, and Gen Z all have in common

They’re all redefining what modern marketing looks like. 

At SIGNAL, you’ll hear how Spotify scales personalized messaging across 675 million users without losing fidelity or speed. Nextdoor is showing how local connections are getting smarter, faster, and more personal thanks to data-backed engagement strategies. And while Gen Z won’t be on stage, they’re the benchmark—shaping how platforms like Partiful rethink digital engagement to meet new expectations for immediacy, authenticity, and fun. These sessions aren’t just for marketers who want to keep up. They’re for builders who decide what happens next.

Two people engage with a mobile device at Twilio SIGNAL London event.

4. Hear from Satya Nadella, Chairman and Chief Executive Officer at Microsoft

At SIGNAL San Francisco, we are featuring a pre-recorded discussion between Satya Nadella, Chairman and Chief Executive Officer at Microsoft, and Khozema Shipchandler, Chief Executive Officer at Twilio. Microsoft and Twilio share a goal of empowering builders and supporting them through the next wave of innovation. These industry-leading CEOs dive into the modernization of customer engagement through real-world AI use cases and how customer data can inform interactions in real-time.

Before being named Microsoft CEO in February 2014, Nadella held leadership roles in both enterprise and consumer businesses across the company. He was executive vice president of Microsoft’s Cloud and Enterprise group. Before that, he led R&D for the Online Services Division and was vice president of the Microsoft Business Division. Before joining Microsoft, Nadella was a member of the technology staff at Sun Microsystems. 

Originally from Hyderabad, India, Nadella lives in Bellevue, Washington, with his family. He earned a bachelor’s degree in electrical engineering from Mangalore University, a master’s degree in computer science from the University of Wisconsin – Milwaukee and a master’s degree in business administration from the University of Chicago. Nadella serves on the board of trustees to his alma mater the University of Chicago. 

5. Build a system that saves lives

A missed call can mean a missed diagnosis. For patients with chronic conditions, the first ring is often the most important. That’s why CareSignal turned to Twilio Branded Calling—to help chronic care teams actually reach the people they’re trying to support. It’s one of several sessions at SIGNAL where purpose meets execution. You’ll also hear from MaineHealth on replacing rigid legacy systems with adaptable outreach, and from Tech Matters on building a contact center designed around empathy, not just efficiency. 

These organizations aren’t optimizing for clicks. They’re using communication infrastructure to save lives, support vulnerable communities, and make their missions scale. Learn how you can do the same this year.

Two women working together on a laptop at a table, one holding a coffee cup, in a public indoor space.

 

6. Step into our lab

Some of the smartest thinking at SIGNAL won’t just be on the main stage; it’ll be happening across the floor. This year’s sponsors are more than logos. They’re shipping real tools, running real experiments, and sharing real-world insights you’ll want to steal. Stop by the booths to chat with teams from companies like Amplitude, Airship, MACH Alliance, MiaRec, Zennify, and more. Then catch their lightning talks on everything from AI agent orchestration to multichannel personalization to why nobody answers the phone anymore unless you’re doing it right. Whether you're hunting for your next integration or just curious where the industry is headed, you’ll find it in the booths where the builders… assemble. (Had to, sorry.

7. See what everyone else will be talking about next quarter

We saved the best for last. Attending SIGNAL means hearing about tomorrow today. And our two keynotes are where we do it.

Day One is all about vision. You’ll hear from Twilio leaders and companies like CLEAR, Best Buy, and UNOS as they share how they’re reaching their customers today. You’ll also be first to hear about our new partnership with Microsoft and what it means for the future of building with AI.

Day Two dives deeper into the tech. Expect thoughtful insight from Twilio’s engineering and product teams, plus appearances from brands like Vineyard Vines and more. It’s a look at how data, infrastructure, and trust come together—and how today’s builders are defining the next generation of customer experience. 

This isn’t vision for vision’s sake. It’s your roadmap for what’s possible, delivered by the people setting the pace.

Woman holding a phone, sitting among other attendees during a conference.

The future belongs to those who build it 

And SIGNAL 2025 is where you lay the foundation to those castles in the sky.

 Whether you're writing the code, shaping the strategy, or keeping up with the latest in customer engagement, this is where ideas get solid. Come for the keynotes, stay for the demos, leave with a notebook full of plans.

Builders, let’s assemble. 

👉Register today!